Polynucleotide Treatments

Polynucleotide Treatments

Polynucleotide injections are an advanced regenerative skin treatment designed to improve skin quality at a cellular level. Rather than adding volume or changing facial shape, polynucleotides work by supporting tissue repair, hydration, and skin resilience. At our Birmingham clinic, polynucleotide treatments are offered as part of a specialist-led, outcome-focused approach to skin rejuvenation, tailored to individual skin concerns and long-term skin health.

Polynucleotides are particularly suited to patients who want natural, progressive improvement in skin quality and structure, without the appearance of having “had work done”.

What are polynucleotides?

Polynucleotides are injectable compounds derived from purified DNA fragments. When placed into the skin, they act as bio-stimulators, supporting cellular repair and encouraging healthier skin function.

Unlike dermal fillers, polynucleotides do not add volume. Unlike traditional skin boosters, their primary role is regeneration rather than hydration alone. They are often chosen for delicate or compromised skin where strength, elasticity, and recovery are the main concerns.

How polynucleotide injections work

Polynucleotides are injected into the superficial and mid-dermal layers of the skin using precise techniques. Once placed, they:

  • Support cellular repair and renewal
  • Improve skin elasticity and texture
  • Enhance hydration at a cellular level
  • Strengthen the skin barrier

The skin responds gradually as biological processes are stimulated. Results develop over weeks rather than days, making polynucleotides a treatment best suited to patients seeking refined, long-term improvement.

Who are polynucleotide treatments for?

Polynucleotide injections are suitable for individuals who:

  • Have thinning, fragile, or crepey skin
  • Are experiencing early to moderate signs of ageing
  • Have dull, tired, or stressed skin
  • Want regenerative treatment without volume
  • Prefer subtle, natural-looking outcomes

They are commonly chosen by patients who are not suitable for fillers, or who want to strengthen skin quality before or alongside other aesthetic treatments.

Areas that polynucleotides can treat

Polynucleotide treatments are highly versatile and can be used in areas where skin quality is particularly delicate:

Face

  • Under-eye area
  • Cheeks
  • Lower face
  • Perioral lines

Neck and décolletage

  • Crepey or thinning skin
  • Fine lines and texture concerns

Body

  • Hands
  • Areas of fragile or sun-damaged skin

Treatment plans are always tailored following detailed assessment of skin condition and anatomy.

How many sessions are needed?

Polynucleotide treatments are delivered as a course, with results building gradually.

  • Typically 2 to 3 sessions
  • Sessions spaced 2 to 4 weeks apart
  • Maintenance treatments may be recommended depending on skin response and ageing process

Your practitioner will advise on the most appropriate schedule following consultation.

Polynucleotides vs other injectable skin treatments

Polynucleotides differ from other injectables in several key ways:

  • They focus on regeneration, not volume
  • They are well suited to delicate or compromised skin
  • They support skin strength and resilience
  • Results are gradual and understated

They can be used alone or alongside treatments such as skin boosters or Profhilo® as part of a comprehensive skin strategy.

Polynucleotide treatments in Birmingham

Patients visit our Birmingham clinic from Edgbaston, Harborne, Moseley, Kings Heath, Sutton Coldfield, Solihull, and across the West Midlands for specialist-led polynucleotide treatments.

Our approach is defined by:

  • Experienced practitioner assessment
  • Bespoke treatment planning
  • Precision injection techniques
  • Focus on long-term skin outcomes

We prioritise skin health, safety, and refined results over trends or aggressive treatments.

Frequently asked questions

Are polynucleotides dermal fillers?
No. Polynucleotides do not add volume or reshape facial features. They improve skin quality through regeneration.

When will I see results from polynucleotide injections?
Results develop gradually over several weeks as the skin responds biologically.

Is there downtime after treatment?
Downtime is usually minimal. Mild swelling, redness, or small injection marks can occur temporarily.

Are polynucleotides suitable for the under-eye area?
Yes. Polynucleotides are often chosen for the under-eye area due to their regenerative properties and suitability for delicate skin, following assessment.

Can polynucleotides be combined with other treatments?
Yes. They are commonly combined with other skin treatments as part of a tailored, outcome-focused plan.

Are polynucleotide treatments suitable for men?
Yes. Polynucleotide treatments are suitable for all genders following appropriate consultation.


Polynucleotide injections – summary

Polynucleotide injections are an advanced regenerative treatment designed to strengthen, repair, and improve skin quality without adding volume or altering facial structure. When delivered by an experienced practitioner, they offer subtle, natural-looking improvements that support long-term skin health.

For patients seeking refined, specialist-led skin rejuvenation in Birmingham, polynucleotides represent a powerful and sophisticated approach to improving skin resilience and quality over time.

How the 8 Point Face Lift Works

Facial changes happen gradually, often due to a combination of reduced collagen, fat redistribution, and bone resorption.

The 8 Point Face Lift is designed to address these changes by targeting key support points rather than focusing only on wrinkles.

It’s a structured, subtle approach intended to provide a refreshed and more supported appearance without surgery.

The 8 Key Lift Points

Each point is selected to provide strategic lift and support:

  1. Upper cheek support
  2. Cheekbone enhancement
  3. Under-eye support
  4. Nasolabial fold support
  5. Marionette line support
  6. Pre-jowl area
  7. Lower cheek contour
  8. Chin support

Placement and product choice are tailored during your consultation to suit your facial structure and objectives.

Expected Outcomes

While individual results vary, this treatment is intended to:

  • Restore mid-face and jawline support
  • Soften lines and folds
  • Improve facial balance and symmetry
  • Provide a refreshed appearance

Treatment typically takes 30–45 minutes. Recovery is usually minimal, allowing most people to resume normal activities quickly.

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T R Trishna profile picture
T R Trishna
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I recently had lip filler and jawline filler done, and I couldn’t be happier with the results! My lips look beautifully shaped and natural, with just the right amount of volume. The jawline filler gave me a more defined and lifted look, which really boosted my confidence. The practitioner was very professional and made me feel comfortable throughout the whole process, explaining each step clearly. Minimal swelling and the results look amazing — natural but noticeable in the best way. Highly recommend for anyone thinking about subtle, refined enhancement!
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Raz B
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I recently had the pleasure of visiting Rose who truly exceeded my expectations using advanced injection techniques on my jaw and cheeks. Rose took the time to thoroughly assess my facial structure and discuss my aesthetic goals, making me feel confident that I was in capable hands. Her expertise was evident in the way Rose tailored the treatment to suit my individual needs, which spoke volumes about her understanding of facial aesthetics. She knows her stuff! During the procedure, I felt comfortable and at ease. Rose demonstrated a high level of skill and precision, employing advanced techniques that resulted in a natural yet enhanced look. I am thrilled with the results. My face looks more contoured and youthful, and I've received numerous compliments on my appearance. Overall, I cannot recommend Rose enough. Thank you!
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Anna D'Bejon
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Rose was super sweet n warm throughout the whole service, can’t wait for my pretty freckles to heal before carnival xx
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Marie Johnson
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Highly recommended! I was unhappy with the shape and how my eyebrows looked so decided to get them microbladed. Rose was so welcoming and informed me of the whole procedure step by step, she is very professional at what she does. I am so happy with how my eyebrows look now, they have turned out much better than I expected. They look so natural. I can’t stop looking in the mirror! Thank you Rose :)
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Keiley Bayliss
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Absolutely beautiful results from an equally beautifully skilled aesthetician
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Julie Baigex
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Visited yesterday, great experience. The lady knows her stuff, treatment plan set up, I had jawline filler and Nasolabial filler, I'm of a mature age, it has transformed my face, really happy with results, procedure I never even flinched, looking forward to 2 week review to get lower face Botox too, Rosie looks at your face and tells you what you'd benefit from, and she was right. All at affordable prices. Mature ladies get booking I feel and look like a spring chicken 😊😊😊, you'll thank me later 😉😉
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Selina Janagil
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Rose was warm and friendly and professional. She gave valuable advice and knew what she was doing 🙂
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Gherasim Bia
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Got my eyebrows microblading done today and I'm so happy with how natural and pretty it looks! Plus, I got tons of great tips and advice! I totally recommend it.
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Safia Begum
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Such good experience rose made feel comfortable explained step by step what she’s gona do to help me look my best would recommend to anyone